Health Research Program
Evaluation of a systems analysis and improvement approach to optimize PMTCT using the consolidated framework for implementation research
Despite large investments to prevent mother-to-child-transmission (PMTCT), pediatric HIV elimination goals are not on track in many countries. The Systems Analysis and Improvement Approach (SAIA) study was a cluster-randomized trial to test whether a package of systems engineering tools could strengthen PMTCT programs. The authors sought to (1) define core and adaptable components of the SAIA intervention, and (2) explain the heterogeneity in SAIA’s success between facilities.